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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK16
All Species:
25.76
Human Site:
S146
Identified Species:
47.22
UniProt:
Q00536
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00536
NP_006192.1
496
55716
S146
P
I
F
D
K
P
L
S
R
R
L
R
R
V
S
Chimpanzee
Pan troglodytes
XP_521035
762
83144
S412
P
I
F
D
K
P
L
S
R
R
L
R
R
V
S
Rhesus Macaque
Macaca mulatta
XP_001100911
485
54881
L143
R
R
L
R
R
V
S
L
S
E
I
G
F
G
K
Dog
Lupus familis
XP_538015
500
56072
S150
P
I
F
D
K
P
L
S
R
R
L
R
R
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q04735
496
55895
S146
P
I
F
D
K
P
L
S
R
R
L
R
R
V
S
Rat
Rattus norvegicus
Q63686
496
55746
S146
P
I
G
D
K
P
L
S
R
R
L
R
P
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521338
549
61821
S199
P
L
F
D
K
P
L
S
R
R
L
R
R
V
S
Chicken
Gallus gallus
XP_416161
516
58803
S173
P
P
F
D
Q
P
M
S
R
R
S
R
R
A
S
Frog
Xenopus laevis
Q6DJM7
435
49211
N123
F
K
G
K
S
K
V
N
G
K
L
V
A
L
K
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
I105
V
Y
K
G
I
S
R
I
N
G
H
L
V
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48609
294
33162
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
89.3
97.5
N.A.
97.5
95.5
N.A.
76.1
69.1
45.1
41.9
N.A.
35.4
N.A.
N.A.
N.A.
Protein Similarity:
100
60.8
90.3
98
N.A.
98.9
97.3
N.A.
81
82.9
59.6
55.8
N.A.
43.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
86.6
N.A.
93.3
66.6
6.6
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
86.6
N.A.
100
80
33.3
0
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
33
N.A.
33.4
N.A.
N.A.
Protein Similarity:
N.A.
45.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
54
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
8
0
47
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
16
8
0
0
0
0
8
8
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
39
0
0
8
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
8
8
8
47
8
0
0
0
8
0
0
0
0
16
% K
% Leu:
0
8
8
0
0
0
47
8
0
0
54
8
0
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
54
8
0
0
0
54
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
8
8
0
8
0
54
54
0
54
47
0
0
% R
% Ser:
0
0
0
0
8
8
8
54
8
0
8
0
0
0
54
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
8
8
0
0
0
0
8
8
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _